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NAD⁺

Longevity · Cellular

NAD⁺

From AED 320.00

The longevity workhorse, coenzyme for mitochondrial energy, sirtuin signaling, and DNA repair.
  • SKUNC-NAD-500
  • StatusBackordered
  • FormatLyophilized vial
  • VerificationCOA included
Also available as NuroPen™
Out of stock

This compound is temporarily unavailable. Restock dates vary by lot; leave your email and we will notify you the moment it ships.

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— About

NAD⁺ is a vital coenzyme present in every cell, essential for energy metabolism, mitochondrial function, and DNA repair. Research highlights its role in cellular longevity, metabolic health, and neuroprotection, a cornerstone compound in anti-aging and performance science.

Secure · SSL encrypted
  • cGMP-certified manufacturing partner
  • Independent COA · ≥99% purity
  • Cold-chain dispatch · 1-3 day UAE delivery
  • Discreet, unlabeled outer packaging
Shipping & delivery

Cold-chain dispatched within 1–3 business days from Abu Dhabi. UAE delivery 1–3 days; GCC 3–5 days; international 7–21 days where lawful. Free UAE delivery on orders over AED 900.

Quality & testing

Sealed lyophilized peptide powder under inert atmosphere. No fillers, no flow agents, no excipients beyond the standard lyo cake matrix. Each batch is independently lab-tested for purity (HPLC), identity (mass spec), heavy metals, and microbial load. Batch-matched Certificates of Analysis are available on request to verified buyers, email [email protected] with your order number.

Storage & handling

Lyophilized vials are stable at room temperature in the original packaging. Once reconstituted, store refrigerated (2–8°C) and use within the compound's stability window. The Dosage Calculator notes per-compound stability.

— Tools for this compound

Calculate dose Reconstitution math + syringe units Read the deep-dive Mechanism, research, contraindications Build a stack Get a curated protocol that includes this

— Why this compound

A coenzyme present in every cell. The substrate longevity research keeps coming back to.

— How it works

Mechanism & pathways

Nicotinamide adenine dinucleotide functions as a redox cofactor in every mitochondrion, shuttling electrons through the citric acid cycle and oxidative phosphorylation chain. Cellular NAD+ levels decline measurably with age, and the literature has linked that decline to reduced sirtuin activity, impaired DNA-damage response, and slower mitochondrial turnover.

Beyond its redox role, NAD+ is the obligate substrate for sirtuin deacetylases and PARP enzymes. Sirtuin activity modulates gene expression around metabolic stress, inflammation, and circadian rhythm. PARPs draw heavily on the NAD+ pool during DNA-damage repair, which is why oxidative stress accelerates depletion.

Research interest sits at the intersection of these two roles: restoring intracellular NAD+ pools to support both energy metabolism and the regulatory enzymes that depend on it.

— Research focus

What the literature looks at

Research-framed mechanisms studied for this compound. Citations below describe published work; they do not represent product claims.

Mitochondrial energy

Research suggests NAD+ availability is rate-limiting for the electron transport chain. Studies report improved mitochondrial respiration in aged tissue with restored cofactor levels.

Sirtuin signaling

Sirtuins require NAD+ as substrate. The literature describes sirtuin-mediated effects on metabolic stress response, inflammation, and longevity-associated gene expression.

DNA repair pathways

PARP-1 enzymes consume NAD+ during single-strand break repair. Studies indicate adequate NAD+ levels support a more responsive DNA-damage repair process.

Cellular senescence

Senescent cell populations show altered NAD+ metabolism. Preclinical research investigates whether restoring NAD+ pools can shift senescence-associated secretory phenotype dynamics.

— Operational notes

Reconstitution & protocol

  1. 01

    Reconstitute

    Add bacteriostatic water to the lyophilized vial along the wall, never directly onto the cake. Swirl gently, do not shake. Powder should fully dissolve into a clear solution.

  2. 02

    Store

    Refrigerate (2–8 °C) immediately after reconstitution. Keep upright in the original packaging away from light. Lyophilized vials stay stable at room temperature in their original sealed packaging.

  3. 03

    Protocol window

    Use within the compound stability window noted on the COA. Protocols vary by compound, see the Dosage Calculator for per-compound timing and the Ingredient Library entry for research-grade reference ranges.

  4. 04

    Stability

    Reconstituted shelf life is compound-specific. Discard the vial if the solution shows visible cloudiness, particulates, or color change. The Calculator notes per-compound stability windows.

Calculate your dose

Related products

— Published research

Selected citations

Citations below describe published research on the compound. They do not represent claims about NuroCore products.

  1. 01
    NAD+ in Aging, Metabolism, and Neurodegeneration

    Comprehensive review of NAD+ biology, age-related decline mechanisms, and therapeutic intervention models.

  2. 02
    Therapeutic Potential of Boosting NAD+ in Aging and Age-Related Diseases

    Maps the link between intracellular NAD+, mitochondrial function, and the sirtuin / PARP axis.

  3. 03
    NAD+ Metabolism: Bioenergetics, Signaling, and Manipulation for Therapy

    Reviews substrate flux, cellular distribution, and the consequences of cofactor depletion.

  4. 04
    Sirtuins, Aging, and Longevity (review)

    Sets out the dependence of the sirtuin family on NAD+ and connects activity to metabolic regulation.

— Frequently asked

Questions, answered.

Are your products safe?

Every batch is independently tested for purity, identity, heavy metals, and microbial contamination before it ships. Formulations use clinical-evidence doses, not under-doses dressed up as a "complex". For any specific medical concern, please consult a qualified healthcare professional.

How fast does delivery arrive in the UAE?

Most UAE orders arrive within 1–3 business days. Cold-chain dispatched, discreet packaging. Cash on Delivery is available across the UAE if you'd rather not share card details online.

Do you ship internationally?

Yes, where lawful. GCC countries typically arrive in 3–5 business days; further international destinations in 7–21 days depending on customs. Buyers are responsible for confirming legality of import in their jurisdiction.

Is the checkout secure?

Yes. The site uses bank-level encryption end to end. Payments run through Ziina (UAE-licensed) and Tabby (regulated BNPL); we never see card data on our servers. Cash on Delivery is also available across the UAE.

Will my order arrive discreetly?

Yes. Outer packaging is unmarked, with no NuroCore branding, no compound names, and no health-product references. Just a plain shipping carton. Your privacy is part of the product.

— Continued reading

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