Tuftsin analog peptide (heptapeptide with Gly-Gly extension)
Selank
Russian anxiolytic peptide studied for stress regulation without sedation.
- Half-life~30 minutes intranasal
- Dose range250 to 500 mcg per spray, 2 to 3 times daily · 2 to 4 week cycle
- Reconstituted stability28 days, 2–8 °C
- VerificationCOA included
Mechanism
How it works.
Modulates GABA-A receptor activity. Effects on serotonin and dopamine signalling. Anxiolytic profile without motor impairment.
Research
What the research shows.
Russian clinical research shows reduced anxiety-related symptoms in adults with generalised anxiety. No sedation, no measurable dependence.
Selank is a synthetic tuftsin analog developed at the Russian Academy of Sciences in the 1990s. The molecule is a stabilised version of the natural immunopeptide tuftsin, with structural modifications that extend plasma half-life past peptidase cleavage.
The compound is anxiolytic without the sedation of benzodiazepines. Russian clinical research base is meaningful; Western replication is more limited. Most-studied delivery route is intranasal.
Contraindications
When not to use.
Active mania or psychosis. Pregnancy. Pediatric use without clinical oversight.
Optimal pairings
Stacks well with.
Information is educational, derived from published research. Not medical advice. All compounds sold for research use only. Bloodwork and a clinical consultation should precede any new protocol.