NuroCore
Semax
Semax
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Semax is a synthetic heptapeptide analog of ACTH(4–10) developed in Russia for its nootropic, neuroprotective, and neurotrophic properties. It is primarily researched for enhancing memory, focus, and neuroplasticity, while also providing neuroprotection in ischemic and oxidative stress conditions. Within the NuroCore framework, Semax is positioned in the Cognitive & Neuroprotection Optimization category.
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Quick Specifications
Concentration (common vials): 5 mg lyophilized powder or nasal spray formulations
Composition: Heptapeptide fragment of adrenocorticotropic hormone (ACTH 4–10 analog)
Formulation: Lyophilized acetate salt or intranasal solution
Half-Life: ~20–30 minutes plasma; extended effects via BDNF modulation
Primary Actions: Nootropic, neuroprotection, BDNF upregulation, cognitive enhancement
Research Highlights
Enhances cognitive performance, memory, and learning in both healthy subjects and patients with cognitive decline.
Upregulates BDNF (Brain-Derived Neurotrophic Factor), promoting neuroplasticity.
Shows neuroprotective benefits in ischemia and oxidative stress models.
Exhibits anti-inflammatory and anxiolytic effects, improving stress resilience.
Reconstitution & Handling
- Reconstitute lyophilized Semax with bacteriostatic water (NuroCore recommended).
Swirl gently until dissolved; avoid shaking.
Administered via intranasal spray (most common research route) or subcutaneous injection.
Vial Storage & Stability
Unreconstituted: Store at –20 °C for up to 24 months.
Reconstituted: Refrigerate at 2–8 °C; use within 10–14 days.
Appearance: Clear, colorless solution after mixing; discard if cloudy or particulate.
Usage & Compliance
Category: Cognitive & Neuroprotection Optimization (NuroCore)
Use Case: Research into cognitive enhancement, neuroprotection, and stress resilience.
Compliance Note: Research peptide only; not for pharmaceutical use without proper regulatory approval.
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