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NuroCore

PT‑141 (Bremelanotide)

PT‑141 (Bremelanotide)

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PT-141, also known as Bremelanotide, is a synthetic melanocortin receptor agonist derived from Melanotan II. Unlike PDE-5 inhibitors (e.g., Viagra), PT-141 works through the central nervous system, making it a unique research compound for enhancing libido, sexual function, and arousal in both men and women. Within the NuroCore framework, PT-141 sits in the Performance & Vitality Optimization category.

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Concentration (common vials): 10 mg lyophilized powder


Composition: Synthetic cyclic heptapeptide, melanocortin receptor agonist


Formulation: Lyophilized acetate salt for reconstitution


Half-Life: ~2.5 hours plasma; central effects may last up to 12 hours


Primary Actions: Increases sexual desire, arousal, and erectile function

Shown to enhance sexual arousal in both men and women via central melanocortin pathways.


Distinct from PDE-5 inhibitors — effective even without direct vascular stimulation.


Studied for treatment of hypoactive sexual desire disorder (HSDD).


Demonstrates rapid onset of action, with effects noticeable within 30–60 minutes.

Reconstitute with bacteriostatic water (NuroCore UAE standard).


Add diluent slowly, swirl gently until clear (avoid shaking).


Administered subcutaneously using insulin syringes for precise dosing

  • Unreconstituted: Store at –20 °C for up to 24 months.

  • Reconstituted: Refrigerate at 2–8 °C; stable for 10–14 days.

  • Appearance: Clear, colorless solution after mixing; discard if cloudy.

Category: Performance & Vitality Optimization (NuroCore UAE)


Use Case: Research into sexual arousal, libido enhancement, and erectile function.


Compliance Note: Approved clinically in some regions (as Vyleesi); cataloged here strictly as a research peptide.